Approved Studies sorted on Review Date

ACTIVE STUDY: The Role of Sex and Age on Intestinal Permeability, the Gut Microbiota, and Endothelial Function

Approval Status: Approved
Number: 159
Submission Date April 17, 2025
Is this study IRB-Approved? Yes
Date of NEXT IRB Review: [294]
Full Study Name: The Role of Sex and Age on Intestinal Permeability, the Gut Microbiota, and Endothelial Function
Short Study Name: Gut Permeability Study
College / Affiliation College of Health Sciences
Relevant Research Categories [328]
Location of Study: University of Delaware STAR Campus, 540 S College Ave, Newark, DE 19713
Description of Study:

The purpose of the study is to determine how age and sex affect the relation between gut permeability, or “gut leakiness”, the gut bacteria, and blood vessel function.

Will participants be compensated for participation?
Inclusion and Exclusion Criteria:

We are looking for men and women between the ages of 30-45 years or 55-70 years.

You would be unable to participate if you have any of the following health conditions:
• High blood pressure (≥140/90 mmHg), a
• BMI greater than 30 or less than 19
• Diabetes
• Heart, kidney, or gastrointestinal diseases
• History of cancer
• History of gastrointestinal surgery or absorption disorders.

You would also be unable to participate if you:
• Smoke tobacco products
• Are currently pregnant or breastfeeding
• Are a trained endurance athlete
• Have taken antibiotics, probiotic supplements, or prebiotic supplements (fiber supplements) in the last 3 months
• Have used hormonal birth control in the last 6 months
• Have undergone hormone replacement therapy
• Take non-steroidal anti-inflammatory drugs (NSAIDs) >3 days/week

“How to Apply” Description:

If you’re interested, please follow the link (https://redcap.chrc.udel.edu/redcap/surveys/?s=PLDEMYX9N4JFN8JR) to a brief eligibility survey. Once you complete the survey, a member of the research team will reach out to you.

How to Apply Link: https://redcap.chrc.udel.edu/redcap/surveys/?s=PLDEMYX9N4JFN8JR
How to Apply Email: kkaseman@udel.edu
Contact Name: Kate
Contact Last Lennon
Contact Email: kkaseman@udel.edu
Phone: 9413566705
PI Name: Shannon
PI Last Lennon
PI Email: slennon@udel.edu